BDBM384124 1-(3-(3-chloro- phenyl)-1H- pyrazolo[3,4-b]- pyrazin-6-yl)-4- methylpiperidin-4- amine::US10280171, Example 10::US10851110, Example 10::US11466017, Example 10::US11529347, Compound 31

SMILES CC1(N)CCN(CC1)c1cnc2c(n[nH]c2n1)-c1cccc(Cl)c1

InChI Key InChIKey=NHGRNRILMHNSIR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384124   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM384124(1-(3-(3-chloro- phenyl)-1H- pyrazolo[3,4-b]- pyraz...)
Affinity DataIC50:  172nMAssay Description:KYSE-520 cells (10 k cells/well) were grown in 384-well plate in 20 uL of medium (RPMI-1640, without phenol red, containing 10% FBS) at 37° C. with 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent