BDBM384124 1-(3-(3-chloro- phenyl)-1H- pyrazolo[3,4-b]- pyrazin-6-yl)-4- methylpiperidin-4- amine::US10280171, Example 10::US10851110, Example 10::US11466017, Example 10::US11529347, Compound 31
SMILES CC1(N)CCN(CC1)c1cnc2c(n[nH]c2n1)-c1cccc(Cl)c1
InChI Key InChIKey=NHGRNRILMHNSIR-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384124
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 172nMAssay Description:KYSE-520 cells (10 k cells/well) were grown in 384-well plate in 20 uL of medium (RPMI-1640, without phenol red, containing 10% FBS) at 37° C. with 5...More data for this Ligand-Target Pair